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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFATC1 All Species: 10.61
Human Site: S848 Identified Species: 29.17
UniProt: O95644 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95644 NP_006153.2 943 101243 S848 S L C P S S P S P P L P P A T
Chimpanzee Pan troglodytes XP_512184 703 76715 S609 G H N F L Q D S K V I F V E K
Rhesus Macaque Macaca mulatta XP_001088054 930 100304 S835 S L C P S S P S P P L P P A A
Dog Lupus familis XP_541045 949 102463 S833 A L C P D S P S S S P P S G P
Cat Felis silvestris
Mouse Mus musculus O88942 717 77815 L623 V L S G H N F L Q D S K V I F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509446 847 89309 P753 P V G G G G S P P P G P S A G
Chicken Gallus gallus XP_418906 927 102137 S832 T L Y P N S P S S P V P S V T
Frog Xenopus laevis NP_001085919 704 78205 L610 I G G K K M I L N G H N F H P
Zebra Danio Brachydanio rerio NP_001038624 867 94251 P773 T G S N A S S P G S H P S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 93.7 75.5 N.A. 67.4 N.A. N.A. 44.8 74.9 54.7 54.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71.7 94.8 82 N.A. 71 N.A. N.A. 55.4 83.3 62.8 67.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 46.6 N.A. 6.6 N.A. N.A. 26.6 53.3 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 93.3 53.3 N.A. 13.3 N.A. N.A. 33.3 73.3 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 12 0 0 0 0 0 0 0 0 34 12 % A
% Cys: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 12 0 0 12 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % E
% Phe: 0 0 0 12 0 0 12 0 0 0 0 12 12 0 12 % F
% Gly: 12 23 23 23 12 12 0 0 12 12 12 0 0 12 12 % G
% His: 0 12 0 0 12 0 0 0 0 0 23 0 0 12 0 % H
% Ile: 12 0 0 0 0 0 12 0 0 0 12 0 0 12 0 % I
% Lys: 0 0 0 12 12 0 0 0 12 0 0 12 0 0 12 % K
% Leu: 0 56 0 0 12 0 0 23 0 0 23 0 0 0 0 % L
% Met: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 12 12 12 0 0 12 0 0 12 0 0 0 % N
% Pro: 12 0 0 45 0 0 45 23 34 45 12 67 23 0 34 % P
% Gln: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 23 0 23 0 23 56 23 56 23 23 12 0 45 0 0 % S
% Thr: 23 0 0 0 0 0 0 0 0 0 0 0 0 12 23 % T
% Val: 12 12 0 0 0 0 0 0 0 12 12 0 23 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _